核受体与辅助调节因子PCR芯片 Nuclear Receptors & Coregulators PCR Arra
核受体与辅助调节因子PCR芯片 Nuclear Receptors & Coregulators PCR Arra
核受体与辅助调节因子PCR芯片Nuclear Receptors & Coregulators PCR Arra
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核受体与辅助调节因子RT² Profiler™ PCR Array可以同时测定84个编码核蛋白受体和辅助调节子的基因。芯片中包括甲状腺和类固醇激素受体、视黄醇和维他命D受体以及孤儿受体。核受体活性的辅助激活因子和辅助抑制因子、染色体修饰酶也包含其中。通过实时定量PCR的方法，研究者即能够利用该芯片简单可靠地同时检测核受体和辅助调节因子相关基因的表达。 Nuclear Receptors: Androgen Receptors and Related Molecules: AR, MED14, MED17, MED12, MED4, NR1I3, MED1, MED13, MED24, MED16. Estrogen Receptors and Related Molecules: ESR1, ESR2, NCOA6, PPARGC1B. Glucocorticoid Receptors and Related Molecules: NCOA6, NR3C1. Retinoic Acid Receptors and Related Molecules: HMGA1, NCOA6, RARA, RARB, RARG, RXRA, RXRB, RXRG. Thyroid Hormone Receptors and Related Molecules: BRD8, MED14, MED17, MED12, MED4, NCOA3, NCOA4, NCOA6, NR1D1, NR1H3, NR1I3, NR2F6, MED1, THRA, MED13, MED24, MED16, THRB. Vitamin D Receptors and Related Molecules: MED14, MED17, MED12, MED4, MED1, MED13, MED24, MED16, VDR. Steroid Hormone Receptors: ESRRA, ESRRB, ESRRG, HNF4A, NR0B1, NR0B2, NR1D1, NR1D2, NR1H2, NR1H3, NR1H4, NR1I2, NR2C1, NR2C2, NR2E3, NR2F1, NR2F2, NR2F6, NR3C2, NR4A1, NR5A1, NR6A1, PPARA, PPARD, PPARG, RARA, RARB, RARG, RORA, RXRA, RXRB, RXRG, THRA, THRB, VDR. Other Nuclear Receptors: AHR, TRIP4. Transcription Factors and Regulators: Ligand-dependent Nuclear Receptor Transcription Coactivators: MED14, MED17, HMGA1, MED12, MED4, NCOA6, MED1, PPARGC1A, PPARGC1B, MED13, MED24, MED16. Positive Regulators of Transcription: ARNT, BRD8, CREBBP, ESR2, KAT5, NCOA1, NCOA2, NCOA3, NCOA4, NFKB2, NR1H3, NR1I2, NR1I3, NR2C2, NR2F1, NR5A1, NRIP1, PSMC3, RARA, RXRA, RXRB, TRIP4. Negative Regulators of Transcription: COPS2, HDAC4, HDAC5, HDAC6, HDAC7, NCOR1, NCOR2, NR0B2, NR1D1, NR2F2, PSMC3, PSMC5, THRA, THRB. Other Transcription Factors and Regulators: AHR, AR, ESR1, ESRRA, ESRRB, ESRRG, HDAC1, HDAC2, HDAC3, HNF4A, ITGB3BP, MTA1, NOTCH2, NR0B1, NR1D2, NR1H2, NR1H4, NR2C1, NR2E3, NR2F6, NR3C1, NR3C2, NR4A1, NR6A1, KAT2B, PPARA, PPARD, PPARG, RARB, RARG, RBPJ (RBPSUH), RORA, RXRG, VDR. Chromatin Modification Molecules: Histone Acetylation: KAT5, NCOA1, NCOA3, KAT2B. Histone Deacetylation: HDAC1, HDAC2, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7. Other Chromatin Modification Molecules: ESR1, HMGA1, NCOA6, PPARGC1B. Other Nuclear Receptor Co-regulators: DDX5, TGS1, NONO. |
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